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Heart Institute study sheds light on gene believed to influence heart health

A new study out of the University of Ottawa Heart Institute is shedding light on a mysterious gene believed to influence the health of the heart.

Researchers had initially identified a variant in a gene called SPG7 as a potential contributor to coronary artery disease several years ago, but it was hard to figure out how exactly it related to heart disease.

They now believe the variant heightens the state of inflammation, which affects diabetes and heart disease.

It also makes people more resistant to the toxic side effects of some chemotherapy drugs.

The study was published in Cell Reports.

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